# Laboratory Investigation

**Type:** Journals  
**Canonical URL:** https://scholariq.org/journals/laboratory-investigation/

## Facts

| Field | Value |
| --- | --- |
| APC (USD) | 4,480 |
| Citations | 203,568 |
| h-index | 176 |
| Homepage | https://www.sciencedirect.com/journal/laboratory-investigation |
| Open Access | false |
| ISSN-L | 0023-6837 |
| ISSNs | 0023-6837,1530-0307 |
| OpenAlex ID | https://openalex.org/S137146891 |
| Publisher | Elsevier BV |
| Works | 8,461 |

## Journal papers

Showing 12 of 26.

- [PPAR-γ agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-β](https://scholariq.org/papers/ppar-agonist-attenuates-renal-interstitial-fibrosis-and-inflammation-through/)
- [Generation of endogenous hydrogen sulfide by cystathionine γ-lyase limits renal ischemia/reperfusion injury and dysfunction](https://scholariq.org/papers/generation-of-endogenous-hydrogen-sulfide-by-cystathionine-lyase-limits-renal/)
- [Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis](https://scholariq.org/papers/impaired-mitophagy-triggers-nlrp3-inflammasome-activation-during-the-progression/)
- [The beneficial effects of physical exercise in the brain and related pathophysiological mechanisms in neurodegenerative diseases](https://scholariq.org/papers/the-beneficial-effects-of-physical-exercise-in-the-brain-and-related/)
- [NGAL decreases E-cadherin-mediated cell–cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells](https://scholariq.org/papers/ngal-decreases-e-cadherin-mediated-cell-cell-adhesion-and-increases-cell/)
- [Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma](https://scholariq.org/papers/klotho-a-tumor-suppressor-and-modulator-of-the-wnt-catenin-pathway-in-human/)
- [Interleukin-10 deficiency aggravates kidney inflammation and fibrosis in the unilateral ureteral obstruction mouse model](https://scholariq.org/papers/interleukin-10-deficiency-aggravates-kidney-inflammation-and-fibrosis-in-the/)
- [The interruption of the PDGF and EGF signaling pathways by curcumin stimulates gene expression of PPARγ in rat activated hepatic stellate cell in vitro](https://scholariq.org/papers/the-interruption-of-the-pdgf-and-egf-signaling-pathways-by-curcumin-stimulates/)
- [RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3](https://scholariq.org/papers/rac1-gtp-promotes-epithelial-mesenchymal-transition-and-invasion-of-colorectal/)
- [The roles of oxidative stress, endoplasmic reticulum stress, and autophagy in aldosterone/mineralocorticoid receptor-induced podocyte injury](https://scholariq.org/papers/the-roles-of-oxidative-stress-endoplasmic-reticulum-stress-and-autophagy-in/)
- [Characterization of a murine nonalcoholic steatohepatitis model induced by high fat high calorie diet plus fructose and glucose in drinking water](https://scholariq.org/papers/characterization-of-a-murine-nonalcoholic-steatohepatitis-model-induced-by-high/)
- [Galectin-1 Is Overexpressed in Nasal Polyps under Budesonide and Inhibits Eosinophil Migration](https://scholariq.org/papers/galectin-1-is-overexpressed-in-nasal-polyps-under-budesonide-and-inhibits/)

## Journal top topics

Showing 8 of 25.

- [Cancer Genomics and Diagnostics](https://scholariq.org/topics/cancer-genomics-and-diagnostics/)
- [AI in cancer detection](https://scholariq.org/topics/ai-in-cancer-detection/)
- [Sarcoma Diagnosis and Treatment](https://scholariq.org/topics/sarcoma-diagnosis-and-treatment/)
- [Radiomics and Machine Learning in Medical Imaging](https://scholariq.org/topics/radiomics-and-machine-learning-in-medical-imaging/)
- [Lymphoma Diagnosis and Treatment](https://scholariq.org/topics/lymphoma-diagnosis-and-treatment/)
- [Liver Disease Diagnosis and Treatment](https://scholariq.org/topics/liver-disease-diagnosis-and-treatment/)
- [Pancreatic and Hepatic Oncology Research](https://scholariq.org/topics/pancreatic-and-hepatic-oncology-research/)
- [Breast Cancer Treatment Studies](https://scholariq.org/topics/breast-cancer-treatment-studies/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.