# (2<i>R</i>)-4-Oxo-4-\[3-(Trifluoromethyl)-5,6-dihydro\[1,2,4\]triazolo\[4,3-<i>a</i>\]pyrazin- 7(8<i>H</i>)-yl\]-1-(2,4,5-trifluorophenyl)butan-2-amine:  A Potent, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/2-i-r-i-4-oxo-4-3-trifluoromethyl-5-6-dihydro-1-2-4-triazolo-4-3-i-a-i-pyrazin-7/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Dooseop Kim,Liping Wang,Maria Beconi,George J. Eiermann,Michael H. Fisher,Huaibing He,Gerard J. Hickey,Jennifer E. Kowalchick,Barbara Leiting,Kathryn A. Lyons,Frank Marsilio,Margaret E. McCann,Reshma A. Patel,Aleksandr Petrov,Giovanna Scapin,Sangita B. Patel,Ranabir Sinha Roy,Joseph K. Wu,Matthew J. Wyvratt,Bei B. Zhang,Lan Zhu,Nancy A. Thornberry,Ann E. Weber |
| Citations | 818 |
| DOI | 10.1021/jm0493156 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2hh6h8h |
| OpenAlex ID | https://openalex.org/W2083473802 |
| PMID | 15634008 |
| Type | article |
| Year | 2004 |

## Paper authors

- [Liping Wang](https://scholariq.org/researchers/liping-wang/)

## Paper primary topic

- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)

## Paper topics

- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)
- [Diabetes Treatment and Management](https://scholariq.org/topics/diabetes-treatment-and-management/)
- [Adenosine and Purinergic Signaling](https://scholariq.org/topics/adenosine-and-purinergic-signaling/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.