# A Central Role for Free Heme in the Pathogenesis of Severe Sepsis

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-central-role-for-free-heme-in-the-pathogenesis-of-severe-sepsis/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Rasmus Larsen,Raffaella Gozzelino,Viktória Jeney,László Tokaji,Fernando A. Bozza,André Miguel Japiassú,Dolores Bonaparte,Moisés Marinho Cavalcante,Ângelo Ferreira Chora,Ana Ferreira,Ivo Marguti,Sílvia Cardoso,Nuno Sepúlveda,Ann Smith,Miguel P. Soares |
| Citations | 491 |
| DOI | 10.1126/scitranslmed.3001118 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://arca.fiocruz.br/handle/icict/38710 |
| OpenAlex ID | https://openalex.org/W2102446851 |
| PMID | 20881280 |
| Type | article |
| Year | 2010 |

## Paper authors

- [Fernando A. Bozza](https://scholariq.org/researchers/fernando-a-bozza/)

## Paper primary topic

- [Heme Oxygenase-1 and Carbon Monoxide](https://scholariq.org/topics/heme-oxygenase-1-and-carbon-monoxide/)

## Paper topics

- [Heme Oxygenase-1 and Carbon Monoxide](https://scholariq.org/topics/heme-oxygenase-1-and-carbon-monoxide/)
- [Hemoglobin structure and function](https://scholariq.org/topics/hemoglobin-structure-and-function/)
- [Neonatal Health and Biochemistry](https://scholariq.org/topics/neonatal-health-and-biochemistry/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.