# A Chemical Tuned Strategy to Develop Novel Irreversible EGFR-TK Inhibitors with Improved Safety and Pharmacokinetic Profiles

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-chemical-tuned-strategy-to-develop-novel-irreversible-egfr-tk-inhibitors-with/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Guangxin Xia,Wenteng Chen,Jing Zhang,Jiaan Shao,Yong Zhang,Wei Huang,Leduo Zhang,Weixing Qi,Xing Sun,Bojun Li,Zhixiong Xiang,Chen Ma,Jiajia Xu,Hailin Deng,Yufeng Li,Ping Li,Hong Miao,Han Jiansheng,Yanjun Liu,Jingkang Shen,Yongping Yu |
| Citations | 76 |
| DOI | 10.1021/jm5014659 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q26w9cpc |
| OpenAlex ID | https://openalex.org/W2052490505 |
| PMID | 25409491 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Yong Zhang](https://scholariq.org/researchers/yong-zhang-2/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)
- [Cancer therapeutics and mechanisms](https://scholariq.org/topics/cancer-therapeutics-and-mechanisms/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.