# A common BIM deletion polymorphism mediates intrinsic resistance and inferior responses to tyrosine kinase inhibitors in cancer

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-common-bim-deletion-polymorphism-mediates-intrinsic-resistance-and-inferior/

## Facts

| Field | Value |
| --- | --- |
| Author Names | King Pan Ng,Axel M. Hillmer,Charles Chuah,Wen Chun Juan,Tun Kiat Ko,Audrey S.M. Teo,Pramila Ariyaratne,Naoto Takahashi,Kenichi Sawada,Yao Fei,Sheila Soh,Wah Heng Lee,John W J Huang,John Carson Allen,Xing Yi Woo,Niranjan Nagarajan,Vikrant Kumar,Anbupalam Thalamuthu,Wan Ting Poh,Ai Leen Ang,Hae Tha Mya,Gee Fung How,Li Yi Yang,Liang Piu Koh,Balram Chowbay,Chia-Tien Chang,Veera Sekaran Nadarajan,Wee Joo Chng,Hein Than,Lay Cheng Lim,Yeow Tee Goh,Shenli Zhang,Dianne Poh,Patrick Tan,Ju‐Ee Seet,Mei‐Kim Ang,Noan‐Minh Chau,Quan‐Sing Ng,Daniel S.W. Tan,Manabu Soda,Kazutoshi Isobe,Markus M. Nöthen,Tien Yin Wong,Atif Shahab,Xiaoan Ruan,Valère Cacheux-Rataboul,Wing‐Kin Sung,Eng Huat Tan,Yasushi Yatabe,Hiroyuki Mano,Ross A. Soo,Tan Min Chin,Wan‐Teck Lim,Yijun Ruan,S. Tiong Ong |
| Citations | 556 |
| DOI | 10.1038/nm.2713 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2091134276 |
| PMID | 22426421 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Ross A. Soo](https://scholariq.org/researchers/ross-a-soo/)
- [Wan‐Teck Lim](https://scholariq.org/researchers/wan-teck-lim/)
- [Daniel S.W. Tan](https://scholariq.org/researchers/daniel-s-w-tan/)

## Paper journal

- [Nature Medicine](https://scholariq.org/journals/nature-medicine/)

## Paper primary topic

- [Chronic Myeloid Leukemia Treatments](https://scholariq.org/topics/chronic-myeloid-leukemia-treatments/)

## Paper topics

- [Chronic Myeloid Leukemia Treatments](https://scholariq.org/topics/chronic-myeloid-leukemia-treatments/)
- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.