# A Novel Fc-FGF21 With Improved Resistance to Proteolysis, Increased Affinity Toward β-Klotho, and Enhanced Efficacy in Mice and Cynomolgus Monkeys

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-novel-fc-fgf21-with-improved-resistance-to-proteolysis-increased-affinity/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Shanaka Stanislaus,Randy Hecht,Junming Yie,Todd Hager,Michael Hall,Chris Spahr,Wei Wang,Jennifer Weiszmann,Yang Li,Liying Deng,Dwight Winters,Stephen H. Smith,Lei Zhou,Yuesheng Li,Murielle M. Véniant,Jing Xu |
| Citations | 112 |
| DOI | 10.1210/en.2016-1917 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://academic.oup.com/endo/article-pdf/158/5/1314/14069029/en.2016-1917.pdf |
| OpenAlex ID | https://openalex.org/W2611434197 |
| PMID | 28324011 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Liying Deng](https://scholariq.org/researchers/liying-deng/)

## Paper primary topic

- [Fibroblast Growth Factor Research](https://scholariq.org/topics/fibroblast-growth-factor-research/)

## Paper topics

- [Fibroblast Growth Factor Research](https://scholariq.org/topics/fibroblast-growth-factor-research/)
- [Kruppel-like factors research](https://scholariq.org/topics/kruppel-like-factors-research/)
- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.