# A Phase I Trial of Regional Mesothelin-Targeted CAR T-cell Therapy in Patients with Malignant Pleural Disease, in Combination with the Anti–PD-1 Agent Pembrolizumab

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-phase-i-trial-of-regional-mesothelin-targeted-car-t-cell-therapy-in-patients/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Prasad S. Adusumilli,Marjorie G. Zauderer,Isabelle Rivière,Stephen B. Solomon,Valerie W. Rusch,Roisin E. O’Cearbhaill,Amy Zhu,Waseem Cheema,Navin K. Chintala,Elizabeth Halton,John Pineda,Rocío Pérez-Johnston,Kay See Tan,Bobby Daly,Jose A. Araujo Filho,Daniel Ngai,Erin McGee,A. Vincent,Claudia Diamonte,Jennifer L. Sauter,Shanu Modi,Devanjan Sikder,Brigitte Sénéchal,Xiuyan Wang,William D. Travis,Mithat Gönen,Charles M. Rudin,Renier J. Brentjens,David R. Jones,Michel Sadelain |
| Citations | 578 |
| DOI | 10.1158/2159-8290.cd-21-0407 |
| Fields | Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://aacrjournals.org/cancerdiscovery/article-pdf/11/11/2748/3103184/2748.pdf |
| OpenAlex ID | https://openalex.org/W3179214161 |
| PMID | 34266984 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Roisin E. O’Cearbhaill](https://scholariq.org/researchers/roisin-e-o-cearbhaill/)
- [Charles M. Rudin](https://scholariq.org/researchers/charles-m-rudin/)

## Paper journal

- [Cancer Discovery](https://scholariq.org/journals/cancer-discovery/)

## Paper primary topic

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)

## Paper topics

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)
- [Occupational and environmental lung diseases](https://scholariq.org/topics/occupational-and-environmental-lung-diseases/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.