# A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial Evaluating the Efficacy of Burosumab, an Anti-FGF23 Antibody, in Adults With X-Linked Hypophosphatemia: Week 24 Primary Analysis

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-randomized-double-blind-placebo-controlled-phase-3-trial-evaluating-the/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Karl Insogna,Karine Briot,Erik A. Imel,Peter Kamenický,Mary D. Ruppe,Anthony A. Portale,Thomas J. Weber,Pisit Pitukcheewanont,Hae Il Cheong,Suzanne M. Jan de Beur,Yasuo Imanishi,Nobuaki Ito,Robin Lachmann,Hiroyuki Tanaka,Farzana Perwad,Lin Zhang,Chaoyin Chen,Christina Theodore‐Oklota,Matt Mealiffe,Javier San Martín,Thomas O. Carpenter,on behalf of the AXLES 1 Investigators |
| Citations | 347 |
| DOI | 10.1002/jbmr.3475 |
| Fields | Medicine,Nursing |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://asbmr.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/jbmr.3475 |
| OpenAlex ID | https://openalex.org/W2810290010 |
| PMID | 29947083 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Erik A. Imel](https://scholariq.org/researchers/erik-a-imel/)

## Paper journal

- [Journal of Bone and Mineral Research](https://scholariq.org/journals/journal-of-bone-and-mineral-research/)

## Paper primary topic

- [Parathyroid Disorders and Treatments](https://scholariq.org/topics/parathyroid-disorders-and-treatments/)

## Paper topics

- [Parathyroid Disorders and Treatments](https://scholariq.org/topics/parathyroid-disorders-and-treatments/)
- [Magnesium in Health and Disease](https://scholariq.org/topics/magnesium-in-health-and-disease/)
- [Bone health and treatments](https://scholariq.org/topics/bone-health-and-treatments/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.