# A randomized phase II study of the MEK1/MEK2 inhibitor trametinib (GSK1120212) compared with docetaxel in KRAS-mutant advanced non-small-cell lung cancer (NSCLC)

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-randomized-phase-ii-study-of-the-mek1-mek2-inhibitor-trametinib-gsk1120212/

## Facts

| Field | Value |
| --- | --- |
| Author Names | George R. Blumenschein,Egbert F. Smit,David Planchard,Dongwook Kim,J. Cadranel,Tommaso De Pas,Frank Dunphy,Katalin Udud,Myung‐Ju Ahn,Nasser H. Hanna,Ji Hyun Kim,Julien Mazières,Sang Wan Kim,P. Baas,Erica Rappold,Suman Redhu,A. Puski,Frank Wu,Pasi A. Jänne |
| Citations | 361 |
| DOI | 10.1093/annonc/mdv072 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | http://www.annalsofoncology.org/article/S0923753419315145/pdf |
| OpenAlex ID | https://openalex.org/W2160586729 |
| PMID | 25722381 |
| Type | article |
| Year | 2015 |

## Paper authors

- [George R. Blumenschein](https://scholariq.org/researchers/george-r-blumenschein/)
- [David Planchard](https://scholariq.org/researchers/david-planchard/)
- [Myung‐Ju Ahn](https://scholariq.org/researchers/myung-ju-ahn/)
- [Julien Mazières](https://scholariq.org/researchers/julien-mazieres/)
- [Tommaso De Pas](https://scholariq.org/researchers/tommaso-de-pas/)
- [Pasi A. Jänne](https://scholariq.org/researchers/pasi-a-janne/)

## Paper journal

- [Annals of Oncology](https://scholariq.org/journals/annals-of-oncology/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Fibroblast Growth Factor Research](https://scholariq.org/topics/fibroblast-growth-factor-research/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.