# A rationally engineered cytosine base editor retains high on-target activity while reducing both DNA and RNA off-target effects

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-rationally-engineered-cytosine-base-editor-retains-high-on-target-activity/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Erwei Zuo,Yidi Sun,Tanglong Yuan,Bingbing He,Changyang Zhou,Wenqin Ying,Jing Liu,Wei Wu,Rong Zeng,Yixue Li,Hui Yang |
| Citations | 174 |
| DOI | 10.1038/s41592-020-0832-x |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W3025828224 |
| PMID | 32424272 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Yidi Sun](https://scholariq.org/researchers/yidi-sun/)

## Paper primary topic

- [CRISPR and Genetic Engineering](https://scholariq.org/topics/crispr-and-genetic-engineering/)

## Paper topics

- [CRISPR and Genetic Engineering](https://scholariq.org/topics/crispr-and-genetic-engineering/)
- [Advanced biosensing and bioanalysis techniques](https://scholariq.org/topics/advanced-biosensing-and-bioanalysis-techniques/)
- [Cytomegalovirus and herpesvirus research](https://scholariq.org/topics/cytomegalovirus-and-herpesvirus-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.