# A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/a-small-molecule-inhibitor-of-the-ubiquitin-activating-enzyme-for-cancer/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Marc L. Hyer,Michael A. Milhollen,Jeff Ciavarri,Paul Fleming,Tary Traore,Darshan S. Sappal,Jessica J. Huck,Judy Shi,James M. Gavin,Jim Brownell,Yang Yu,Bradley Stringer,Robert Griffin,Frank J. Bruzzese,Teresa A. Soucy,Jennifer Duffy,Claudia Rabino,Jessica Riceberg,Kara M. Hoar,Anya Lublinsky,Saurabh Menon,Michael D. Sintchak,Nancy J. Bump,Sai Murali Krishna Pulukuri,Steven Langston,Stephen Tirrell,Mike Kuranda,Petter O. Veiby,John Newcomb,Ping Li,Jing Wu,Josh Powe,Lawrence R. Dick,Paul D. Greenspan,Katherine Galvin,Mark Manfredi,Chris Claiborne,Benjamin Amidon,Neil Bence |
| Citations | 461 |
| DOI | 10.1038/nm.4474 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2783151804 |
| PMID | 29334375 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Yang Yu](https://scholariq.org/researchers/yang-yu/)

## Paper journal

- [Nature Medicine](https://scholariq.org/journals/nature-medicine/)

## Paper primary topic

- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways/)

## Paper topics

- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways/)
- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)
- [Autophagy in Disease and Therapy](https://scholariq.org/topics/autophagy-in-disease-and-therapy/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.