# Acquired Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib Is Associated with a Second Mutation in the EGFR Kinase Domain

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/acquired-resistance-of-lung-adenocarcinomas-to-gefitinib-or-erlotinib-is/

## Facts

| Field | Value |
| --- | --- |
| Author Names | William Pao,Vincent A. Miller,Katerina Politi,Gregory J. Riely,Romel Somwar,Maureen F. Zakowski,Mark G. Kris,Harold Varmus |
| Citations | 3,538 |
| DOI | 10.1371/journal.pmed.0020073 |
| Fields | Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.0020073&type=printable |
| OpenAlex ID | https://openalex.org/W2002937040 |
| PMID | 15737014 |
| Type | article |
| Year | 2005 |

## Paper authors

- [Mark G. Kris](https://scholariq.org/researchers/mark-g-kris/)
- [Gregory J. Riely](https://scholariq.org/researchers/gregory-j-riely/)

## Paper journal

- [PLoS Medicine](https://scholariq.org/journals/plos-medicine/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Chronic Myeloid Leukemia Treatments](https://scholariq.org/topics/chronic-myeloid-leukemia-treatments/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.