# Acquired Resistance to the Mutant-Selective EGFR Inhibitor AZD9291 Is Associated with Increased Dependence on RAS Signaling in Preclinical Models

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/acquired-resistance-to-the-mutant-selective-egfr-inhibitor-azd9291-is-associated/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Catherine A. Eberlein,Daniel Stetson,Aleksandra Markovets,Katherine Al-Kadhimi,Zhongwu Lai,Paul R. Fisher,Catherine B. Meador,Paula J. Spitzler,Eiki Ichihara,Sarah J. Ross,Miika Ahdesmäki,Ambar Ahmed,Laura E. Ratcliffe,Elizabeth L. Christey O'Brien,Claire H. Barnes,H. Shelton Brown,Paul D. Smith,Jonathan R. Dry,Garry Beran,Kenneth S. Thress,Brian Dougherty,William Pao,Darren A.E. Cross |
| Citations | 303 |
| DOI | 10.1158/0008-5472.can-14-3167 |
| Fields | Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://cancerres.aacrjournals.org/content/canres/75/12/2489.full.pdf |
| OpenAlex ID | https://openalex.org/W2050211354 |
| PMID | 25870145 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Kenneth S. Thress](https://scholariq.org/researchers/kenneth-s-thress/)

## Paper journal

- [Cancer Research](https://scholariq.org/journals/cancer-research/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)
- [Cytokine Signaling Pathways and Interactions](https://scholariq.org/topics/cytokine-signaling-pathways-and-interactions/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.