# Adjuvant vemurafenib in resected, BRAFV600 mutation-positive melanoma (BRIM8): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/adjuvant-vemurafenib-in-resected-brafv600-mutation-positive-melanoma-brim8-a/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Michele Maio,Michele Maio,Karl Lewis,Lev Demidov,Mario Mandalà,Igor Bondarenko,Paolo A Ascierto,Christopher Herbert,Andrzej Maćkiewicz,Piotr Rutkowski,Alexander Guminski,Grant R. Goodman,Brian Simmons,Chenglin Ye,Yibing Yan,Dirk Schadendorf,Gabriela Cinat,Luis Fein,Michael P. Brown,Alexander Guminski,Andrew Haydon,Adnan Khattak,Catriona M. McNeil,Phillip Parente,Jeremy Power,Rachel Roberts‐Thomson,Shahneen Sandhu,Craig Underhill,Suresh Varma,Thomas Berger,Ahmad Awada,Nathalie Blockx,Véronique Buyse,Jeroen Mebis,Fábio Franke,Sérgio Jobim Azevedo,Nicolas Lazaretti,Rahima Jamal,Catalin Mihalcioiu,Teresa M. Petrella,Kerry J. Savage,Ralph Wong,Ralph Wong,Nina Dabelić,Stjepko Pleština,Željko Vojnović,Petr Arenberger,Ivo Kocák,Ivana Krajsová,Eugen Kubala,Bohuslav Melichar,Yvetta Vantuchová,Kadri Putnik,Brigitte Dréno,Caroline Dutriaux,Jean‐Jacques Grob,P. Joly,J.‐P. Lacour,Nicolás Meyer,Laurent Mortier,L. Thomas,Michael Fluck,Thilo Gambichler,Jessica C. Hassel,Axel Hauschild,Dirk Schadendorf,Paul Donnellan,John McCaffrey,Derek G. Power,Samuel Ariad,Gil Bar‐Sela,Daniel Hendler,Ilan G. Ron,Jacob Schachter,Paolo Ascierto,Alfredo Berruti,Luca Bianchi,Vanna Chiarion‐Sileni,Francesco Cognetti,Riccardo Danielli,Anna Maria Di Giacomo,Luca Gianni,Aron Goldhirsch,Michele Guida,Michele Maio,Michele Maio,Mario Mandalà,Paolo Marchetti,Paola Queirolo,Armando Santoro,Ellen Kapiteijn,Andrzej Mackiewicz,Piotr Rutkowski,P. Ferreira,Lev Demidov,Georgy Gafton,Yulia Makarova,Zoran Andrić,Nada Babović,Darjana Jovanovic |
| Citations | 218 |
| DOI | 10.1016/s1470-2045(18)30106-2 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.sciencedirect.com/science/article/pii/S1470204518301062 |
| OpenAlex ID | https://openalex.org/W2788938550 |
| PMID | 29477665 |
| Type | article |
| Year | 2018 |

## Paper authors

- [Shahneen Sandhu](https://scholariq.org/researchers/shahneen-sandhu/)
- [Luca Bianchi](https://scholariq.org/researchers/luca-bianchi/)

## Paper journal

- [The Lancet Oncology](https://scholariq.org/journals/the-lancet-oncology/)

## Paper primary topic

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)

## Paper topics

- [Melanoma and MAPK Pathways](https://scholariq.org/topics/melanoma-and-mapk-pathways/)
- [Cutaneous Melanoma Detection and Management](https://scholariq.org/topics/cutaneous-melanoma-detection-and-management/)
- [Brain Metastases and Treatment](https://scholariq.org/topics/brain-metastases-and-treatment/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.