# Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/age-stratified-and-blood-pressure-stratified-effects-of-blood-pressure-lowering/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Kazem Rahimi,Zeinab Bidel,Milad Nazarzadeh,Emma Copland,Dexter Canoy,Małgorzata Wamil,Jeannette Majert,Richard J. McManus,Amanda Adler,Larry Agodoa,Ale Algra,Folkert W. Asselbergs,Nigel Beckett,Eivind Berge,Henry R. Black,Eric Boersma,Frank P. Brouwers,Morris J. Brown,Jasper J. Brugts,Christopher J. Bulpitt,Robert P. Byington,William C. Cushman,Jeffrey A. Cutler,Richard B Devereaux,Jamie P. Dwyer,Ray Estacio,Robert Fagard,Kim Fox,Tsuguya Fukui,Ajay Gupta,Rury R. Holman,Yutaka Imai,Masao Ishii,Stevo Julius,Yoshihiko Kanno,Sverre E. Kjeldsen,John B. Kostis,Kizuku Kuramoto,Jan Lanke,Edmund J. Lewis,Julia B. Lewis,Michel Lièvre,Lars Lindholm,Stephan Lueders,Stephen MacMahon,Giuseppe Mancia,Masunori Matsuzaki,Maria H. Mehlum,Steven Nissen,Hiroshi Ogawa,Toshio Ogihara,Takayoshi Ohkubo,Christopher R. Palmer,Anushka Patel,Marc Allan Pfeffer,Bertram Pitt,Neil R Poulter,Hiromi Rakugi,Gianpaolo Reboldi,Christopher M. Reid,Giuseppe Remuzzi,Piero Ruggenenti,Takao Saruta,Joachim Schrader,Robert W. Schrier,Peter Sever,Peter Sleight,Jan A. Staessen,Hiromichi Suzuki,Lutgarde Thijs,Kenji Ueshima,Seiji Umemoto,Wiek H. van Gilst,Paolo Verdecchia,Kristian Wachtell,Paul K. Whelton,Lindon Wing,Mark Woodward,Yoshiki Yui,Salim Yusuf,Alberto Zanchetti,Zhen‐Yu Zhang,Craig S. Anderson,Colin Baigent,Barry M. Brenner,Rory Collins,Dick de Zeeuw,Jacobus Lubsen,Ettore Malacco,Bruce Neal,Vlado Perkovic,Anthony Rodgers,Peter M. Rothwell,Gholamreza Salimi-Khorshidi,Johan Sundström,Fiona Turnbull,Giancarlo Viberti,Ji‐Guang Wang,John Chalmers,Barry R. Davis |
| Citations | 330 |
| DOI | 10.1016/s0140-6736(21)01921-8 |
| Fields | Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | http://www.thelancet.com/article/S0140673621019218/pdf |
| OpenAlex ID | https://openalex.org/W3194290079 |
| PMID | 34461040 |
| Type | review |
| Year | 2021 |

## Paper authors

- [Dick de Zeeuw](https://scholariq.org/researchers/dick-de-zeeuw/)
- [Rury R. Holman](https://scholariq.org/researchers/rury-r-holman/)
- [Neil R Poulter](https://scholariq.org/researchers/neil-r-poulter/)
- [Bruce Neal](https://scholariq.org/researchers/bruce-neal/)
- [Hiromichi Suzuki](https://scholariq.org/researchers/hiromichi-suzuki/)
- [Lars Lindholm](https://scholariq.org/researchers/lars-lindholm/)
- [Giuseppe Remuzzi](https://scholariq.org/researchers/giuseppe-remuzzi/)
- [Vlado Perkovic](https://scholariq.org/researchers/vlado-perkovic/)
- [Bertram Pitt](https://scholariq.org/researchers/bertram-pitt-2/)
- [Richard J. McManus](https://scholariq.org/researchers/richard-j-mcmanus/)

## Paper journal

- [The Lancet](https://scholariq.org/journals/the-lancet/)

## Paper primary topic

- [Blood Pressure and Hypertension Studies](https://scholariq.org/topics/blood-pressure-and-hypertension-studies/)

## Paper topics

- [Blood Pressure and Hypertension Studies](https://scholariq.org/topics/blood-pressure-and-hypertension-studies/)
- [Cardiovascular Health and Disease Prevention](https://scholariq.org/topics/cardiovascular-health-and-disease-prevention/)
- [Renin-Angiotensin System Studies](https://scholariq.org/topics/renin-angiotensin-system-studies/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
