# Algorithm for optimized mRNA design improves stability and immunogenicity

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/algorithm-for-optimized-mrna-design-improves-stability-and-immunogenicity/

## Facts

| Field | Value |
| --- | --- |
| Author Names | He Zhang,Liang Zhang,Ang Lin,Congcong Xu,Ziyu Li,Kaibo Liu,Boxiang Liu,Xiaopin Ma,Fanfan Zhao,Huiling Jiang,Chunxiu Chen,Haifa Shen,Hangwen Li,David H. Mathews,Yujian Zhang,Liang Huang |
| Citations | 459 |
| DOI | 10.1038/s41586-023-06127-z |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://www.nature.com/articles/s41586-023-06127-z_reference.pdf |
| OpenAlex ID | https://openalex.org/W4367681391 |
| PMID | 37130545 |
| Type | article |
| Year | 2023 |

## Paper authors

- [Ziyu Li](https://scholariq.org/researchers/ziyu-li/)

## Paper journal

- [Nature](https://scholariq.org/journals/nature/)

## Paper primary topic

- [RNA and protein synthesis mechanisms](https://scholariq.org/topics/rna-and-protein-synthesis-mechanisms/)

## Paper topics

- [RNA and protein synthesis mechanisms](https://scholariq.org/topics/rna-and-protein-synthesis-mechanisms/)
- [RNA Interference and Gene Delivery](https://scholariq.org/topics/rna-interference-and-gene-delivery/)
- [Viral Infections and Immunology Research](https://scholariq.org/topics/viral-infections-and-immunology-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.