# Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/allosteric-inhibition-of-shp2-identification-of-a-potent-selective-and-orally/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jorge Fortanet,Christine Hiu-Tung Chen,Ying-Nan P. Chen,Zhouliang Chen,Zhan Deng,Brant Firestone,Peter Fekkes,Michelle Fodor,Pascal D. Fortin,Cary Fridrich,Denise C. Grünenfelder,Samuel B. Ho,Kang Zhao,Rajesh Karki,Mitsunori Kato,Nick Keen,Laura R. LaBonte,Jay F. Larrow,François Lenoir,Gang Liu,Shumei Liu,Franco Lombardo,Dyuti Majumdar,Matthew J. Meyer,Mark Palermo,Lawrence Perez,Minying Pu,Timothy M. Ramsey,William R. Sellers,Michael D. Shultz,Travis Stams,Christopher Towler,Ping Wang,Sarah Williams,Ji-Hu Zhang,Matthew J. LaMarche |
| Citations | 296 |
| DOI | 10.1021/acs.jmedchem.6b00680 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology,Pharmacology, Toxicology and Pharmaceutics |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.osti.gov/servlets/purl/1404987 |
| OpenAlex ID | https://openalex.org/W2475259576 |
| PMID | 27347692 |
| Type | article |
| Year | 2016 |

## Paper authors

- [Ping Wang](https://scholariq.org/researchers/ping-wang/)

## Paper primary topic

- [Protein Tyrosine Phosphatases](https://scholariq.org/topics/protein-tyrosine-phosphatases/)

## Paper topics

- [Protein Tyrosine Phosphatases](https://scholariq.org/topics/protein-tyrosine-phosphatases/)
- [Galectins and Cancer Biology](https://scholariq.org/topics/galectins-and-cancer-biology/)
- [Bioactive Compounds and Antitumor Agents](https://scholariq.org/topics/bioactive-compounds-and-antitumor-agents/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.