# Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/allosteric-shp2-inhibitor-iacs-13909-overcomes-egfr-dependent-and-egfr/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Yuting Sun,Brooke A. Meyers,Barbara Czakó,Paul G. Leonard,Faika Mseeh,Angela L. Harris,Qi Wu,Sarah B. Johnson,Connor A. Parker,Jason B. Cross,Maria Emilia Di Francesco,Benjamin J. Bivona,Christopher A. Bristow,Jason P. Burke,Caroline C. Carrillo,Christopher L. Carroll,Qing Chang,Ningping Feng,Guang Gao,Sonal Gera,Virginia Giuliani,Justin K. Huang,Yongying Jiang,Zhijun Kang,Jeffrey J. Kovacs,Chiu-Yi Liu,Anastasia M. Lopez,Xiaoyan Ma,Pijus K. Mandal,Timothy McAfoos,Meredith A. Miller,Robert A. Mullinax,Michael Peoples,Vandhana Ramamoorthy,Sahil Seth,Nakia D. Spencer,Érika Suzuki,Christopher C. Williams,Simon S. Yu,Andy M. Zuniga,Giulio Draetta,Joseph R. Marszalek,Timothy P. Heffernan,Nancy E. Kohl,Philip Jones |
| Citations | 106 |
| DOI | 10.1158/0008-5472.can-20-1634 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/11106563 |
| OpenAlex ID | https://openalex.org/W3085529787 |
| PMID | 32928921 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Xiaoyan Ma](https://scholariq.org/researchers/xiaoyan-ma/)

## Paper journal

- [Cancer Research](https://scholariq.org/journals/cancer-research/)

## Paper primary topic

- [Protein Tyrosine Phosphatases](https://scholariq.org/topics/protein-tyrosine-phosphatases/)

## Paper topics

- [Protein Tyrosine Phosphatases](https://scholariq.org/topics/protein-tyrosine-phosphatases/)
- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.