# An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/an-allosteric-prc2-inhibitor-targeting-the-h3k27me3-binding-pocket-of-eed/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Wei Qi,Kehao Zhao,Justin Gu,Ying Huang,Youzhen Wang,Hailong Zhang,Man Zhang,Jeff Zhang,Zhengtian Yu,Ling Li,Lin Teng,Shannon Chuai,Chao Zhang,Mengxi Zhao,Homan Chan,Zijun Chen,Douglas D. Fang,Qi Fei,Leying Feng,Lijian Feng,Yuan Gao,Hui Ge,Xinjian Ge,Guobin Li,Andreas Lingel,Ying Lin,Yueqin Liu,Fangjun Luo,Minlong Shi,Long Wang,Zhaofu Wang,Yanyan Yu,Jue Zeng,Chenhui Zeng,Lijun Zhang,Qiong Zhang,Shaolian Zhou,Counde O-Yang,Peter Atadja,En Li |
| Citations | 324 |
| DOI | 10.1038/nchembio.2304 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2s75f64 |
| OpenAlex ID | https://openalex.org/W2582081516 |
| PMID | 28135235 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Shannon Chuai](https://scholariq.org/researchers/shannon-chuai/)

## Paper primary topic

- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)

## Paper topics

- [Epigenetics and DNA Methylation](https://scholariq.org/topics/epigenetics-and-dna-methylation/)
- [Cancer-related gene regulation](https://scholariq.org/topics/cancer-related-gene-regulation/)
- [RNA modifications and cancer](https://scholariq.org/topics/rna-modifications-and-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.