# An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/an-als-associated-mutation-affecting-tdp-43-enhances-protein-aggregation-fibril/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Weirui Guo,Yanbo Chen,Xiaohong Zhou,Amar N. Kar,Payal Ray,Xiaoping Chen,Elizabeth J. Rao,Mengxue Yang,Haihong Ye,Li Zhu,Jianghong Liu,Meng Xu,Yanlian Yang,Chen Wang,David Zhang,Eileen H. Bigio,Marsel Mesulam,Yan Shen,Qi Xu,Kazuo Fushimi,Jane Y. Wu |
| Citations | 314 |
| DOI | 10.1038/nsmb.2053 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/3357956 |
| OpenAlex ID | https://openalex.org/W2143612940 |
| PMID | 21666678 |
| Type | article |
| Year | 2011 |

## Paper authors

- [Jianghong Liu](https://scholariq.org/researchers/jianghong-liu/)

## Paper primary topic

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)

## Paper topics

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)
- [Prion Diseases and Protein Misfolding](https://scholariq.org/topics/prion-diseases-and-protein-misfolding/)
- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.