# An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/an-epithelial-mesenchymal-transition-gene-signature-predicts-resistance-to-egfr/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Lauren A. Byers,Lixia Diao,Jing Wang,Pierre Saintigny,Luc Girard,Michael Peyton,Li Shen,You-Hong Fan,Uma Giri,Praveen K. Tumula,Monique B. Nilsson,Jayanthi Gudikote,Hai T. Tran,Robert J. Cardnell,David J. Bearss,Steven L. Warner,Jason M. Foulks,Steven B. Kanner,Varsha Gandhi,Nancy Krett,Steven T. Rosen,Edward S. Kim,Roy S. Herbst,George R. Blumenschein,J. Jack Lee,Scott M. Lippman,K. Kian Ang,Gordon B. Mills,Waun Ki Hong,John N. Weinstein,Ignacio I. Wistuba,Kevin R. Coombes,John D. Minna,John V. Heymach |
| Citations | 1,136 |
| DOI | 10.1158/1078-0432.ccr-12-1558 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/3567921 |
| OpenAlex ID | https://openalex.org/W2169105660 |
| PMID | 23091115 |
| Type | article |
| Year | 2012 |

## Paper authors

- [Lauren A. Byers](https://scholariq.org/researchers/lauren-a-byers/)
- [George R. Blumenschein](https://scholariq.org/researchers/george-r-blumenschein/)
- [Jing Wang](https://scholariq.org/researchers/jing-wang-3/)
- [John V. Heymach](https://scholariq.org/researchers/john-v-heymach/)

## Paper journal

- [Clinical Cancer Research](https://scholariq.org/journals/clinical-cancer-research/)

## Paper primary topic

- [Phagocytosis and Immune Regulation](https://scholariq.org/topics/phagocytosis-and-immune-regulation/)

## Paper topics

- [Phagocytosis and Immune Regulation](https://scholariq.org/topics/phagocytosis-and-immune-regulation/)
- [Pancreatic and Hepatic Oncology Research](https://scholariq.org/topics/pancreatic-and-hepatic-oncology-research/)
- [Liver physiology and pathology](https://scholariq.org/topics/liver-physiology-and-pathology/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.