# ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/apoe4-markedly-exacerbates-tau-mediated-neurodegeneration-in-a-mouse-model-of/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Alzheimer’s Disease Neuroimaging Initiative,Yang Shi,Kaoru Yamada,Shane A. Liddelow,Scott Smith,Lingzhi Zhao,Wenjie Luo,Richard Tsai,Salvatore Spina,Lea T. Grinberg,Julio C. Rojas,Gilbert Gallardo,Kairuo Wang,Joseph Roh,Grace O. Robinson,Mary Beth Finn,Hong Jiang,Patrick M. Sullivan,Caroline Baufeld,Michael W. Wood,Courtney L. Sutphen,Lena McCue,Chengjie Xiong,Jorge L. Del‐Aguila,John C. Morris,Carlos Cruchaga,A. Fagan,Bruce L. Miller,Adam L. Boxer,William W. Seeley,Oleg Butovsky,Ben A. Barres,S. Paul,David M. Holtzman |
| Citations | 1,254 |
| DOI | 10.1038/nature24016 |
| Fields | Medicine,Neuroscience |
| Open Access | true |
| OA Status | green |
| OA URL | http://hdl.handle.net/10161/15694 |
| OpenAlex ID | https://openalex.org/W2756959977 |
| PMID | 28959956 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Bruce L. Miller](https://scholariq.org/researchers/bruce-l-miller/)
- [William W. Seeley](https://scholariq.org/researchers/william-w-seeley/)

## Paper journal

- [Nature](https://scholariq.org/journals/nature/)

## Paper primary topic

- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)

## Paper topics

- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)
- [Neuroinflammation and Neurodegeneration Mechanisms](https://scholariq.org/topics/neuroinflammation-and-neurodegeneration-mechanisms/)
- [Neurological Disease Mechanisms and Treatments](https://scholariq.org/topics/neurological-disease-mechanisms-and-treatments/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.