# Assessment of the beta-adrenergic receptor pathway in the intact failing human heart: progressive receptor down-regulation and subsensitivity to agonist response.

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/assessment-of-the-beta-adrenergic-receptor-pathway-in-the-intact-failing-human/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Michael B. Fowler,J Laser,G L Hopkins,Wayne Minobe,Michael R. Bristow |
| Citations | 565 |
| DOI | 10.1161/01.cir.74.6.1290 |
| Fields | Agricultural and Biological Sciences,Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W1980258822 |
| PMID | 3022962 |
| Type | article |
| Year | 1986 |

## Paper authors

- [Michael B. Fowler](https://scholariq.org/researchers/michael-b-fowler/)

## Paper journal

- [Circulation](https://scholariq.org/journals/circulation/)

## Paper primary topic

- [Pharmacological Effects and Assays](https://scholariq.org/topics/pharmacological-effects-and-assays/)

## Paper topics

- [Pharmacological Effects and Assays](https://scholariq.org/topics/pharmacological-effects-and-assays/)
- [Receptor Mechanisms and Signaling](https://scholariq.org/topics/receptor-mechanisms-and-signaling/)
- [Cardiac electrophysiology and arrhythmias](https://scholariq.org/topics/cardiac-electrophysiology-and-arrhythmias/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.