# Association of High Tumor Mutation Burden in Non–Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/association-of-high-tumor-mutation-burden-in-non-small-cell-lung-cancers-with/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Biagio Ricciuti,Xinan Wang,Joao V. Alessi,Hira Rizvi,Navin R. Mahadevan,Yvonne Y. Li,Andrew Polio,James Lindsay,Renato Umeton,Rileen Sinha,Natalie I. Vokes,Gonzalo Recondo,Giuseppe Lamberti,Marissa Lawrence,Victor R. Vaz,Giulia C. Leonardi,Andrew J. Plodkowski,Hersh Gupta,Andrew D. Cherniack,Michael Tolstorukov,Bijaya Sharma,Kristen D. Felt,Justin F. Gainor,Arvind Ravi,Gad Getz,Kurt A. Schalper,Brian S. Henick,Patrick M. Forde,Valsamo Anagnostou,Pasi A. Jänne,Eliezer M. Van Allen,Mizuki Nishino,Lynette M. Sholl,David C. Christiani,Xihong Lin,Scott J. Rodig,Matthew D. Hellmann,Mark M. Awad |
| Citations | 389 |
| DOI | 10.1001/jamaoncol.2022.1981 |
| Fields | Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://jamanetwork.com/journals/jamaoncology/articlepdf/2793565/jamaoncology_ricciuti_2022_oi_220022_1671559773.22536.pdf |
| OpenAlex ID | https://openalex.org/W4283030292 |
| PMID | 35708671 |
| Type | article |
| Year | 2022 |

## Paper authors

- [Biagio Ricciuti](https://scholariq.org/researchers/biagio-ricciuti/)
- [Matthew D. Hellmann](https://scholariq.org/researchers/matthew-d-hellmann/)
- [Eliezer M. Van Allen](https://scholariq.org/researchers/eliezer-m-van-allen/)
- [Pasi A. Jänne](https://scholariq.org/researchers/pasi-a-janne/)
- [Patrick M. Forde](https://scholariq.org/researchers/patrick-m-forde/)
- [Mizuki Nishino](https://scholariq.org/researchers/mizuki-nishino/)
- [Justin F. Gainor](https://scholariq.org/researchers/justin-f-gainor/)
- [Michael Tolstorukov](https://scholariq.org/researchers/michael-tolstorukov/)
- [Natalie I. Vokes](https://scholariq.org/researchers/natalie-i-vokes/)
- [Lynette M. Sholl](https://scholariq.org/researchers/lynette-m-sholl/)

## Paper journal

- [JAMA Oncology](https://scholariq.org/journals/jama-oncology/)

## Paper primary topic

- [Cancer Immunotherapy and Biomarkers](https://scholariq.org/topics/cancer-immunotherapy-and-biomarkers/)

## Paper topics

- [Cancer Immunotherapy and Biomarkers](https://scholariq.org/topics/cancer-immunotherapy-and-biomarkers/)
- [Lung Cancer Diagnosis and Treatment](https://scholariq.org/topics/lung-cancer-diagnosis-and-treatment/)
- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.