# Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/autoantibodies-neutralizing-type-i-ifns-are-present-in-4-of-uninfected/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Paul Bastard,Adrian Gervais,Tom Le Voyer,Jérémie Rosain,Quentin Philippot,Jérémy Manry,Eleftherios Michailidis,Hans-Heinrich Hoffmann,Shohei Eto,Marina García-Prat,Lucy Bizien,Alba Parra-Martínez,Rui Yang,Liis Haljasmägi,Mélanie Migaud,Karita Särekannu,Julia Maslovskaja,Nicolas de Prost,Yacine Tandjaoui-Lambiotte,Charles‐Édouard Luyt,Blanca Amador-Borrero,Alexandre Gaudet,Julien Poissy,Pascal Morel,Pascale Richard,Fabrice Cognasse,Jesús Troya,Sophie Trouillet‐Assant,Alexandre Bélot,Kahina Saker,Pierre Garçon,Jacques G. Rivière,Jean‐Christophe Lagier,Stéphanie Gentile,Lindsey B. Rosen,Elana Shaw,Tomohiro Morio,Junko Tanaka,David Dalmau,Pierre‐Louis Tharaux,D. Sène,Alain Stépanian,Bruno Mégarbane,Vasiliki Triantafyllia,Arnaud Fekkar,James R. Heath,José Luis Franco,Juan‐Manuel Anaya,Jordi Solé‐Violán,Luisa Imberti,Andrea Biondi,Paolo Bonfanti,Riccardo Castagnoli,Ottavia M. Delmonte,Yu Zhang,Andrew L. Snow,Steven M. Holland,Catherine M. Biggs,Marcela Moncada‐Vélez,Andrés A. Arias,Lazaro Lorenzo,Soraya Boucherit,Boubacar Coulibaly,Dany Anglicheau,Anna M. Planas,Filomeen Haerynck,Sotiriјa Duvlis,Robert L. Nussbaum,Tayfun Özçelık,Sevgi Keleş,Ahmed Aziz Bousfiha,Jalila El Bakkouri,Carolina Ramı́rez-Santana,Stéphane Paul,Qiang Pan‐Hammarström,Lennart Hammarström,Annabelle Dupont,Alina Kurolap,Christine N. Metz,Alessandro Aiuti,Giorgio Casari,Vito Lampasona,Fabio Ciceri,Lucila Akune Barreiros,Elena Domínguez‐Garrido,Mateus Vidigal,Mayana Zatz,Diederik van de Beek,Sabina Sahanic,Ivan Tancevski,Yuriy Stepanovskyy,Oksana Boyarchuk,Yoko Nukui,Miyuki Tsumura,Loreto Vidaur,Stuart G. Tangye,Sonia Burrel,Darragh Duffy,Lluís Quintana‐Murci,Adam Klocperk |
| Citations | 637 |
| DOI | 10.1126/sciimmunol.abl4340 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://doi.org/10.1126/sciimmunol.abl4340 |
| OpenAlex ID | https://openalex.org/W3195130348 |
| PMID | 34413139 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Qiang Pan‐Hammarström](https://scholariq.org/researchers/qiang-pan-hammarstrom/)

## Paper primary topic

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)

## Paper topics

- [SARS-CoV-2 and COVID-19 Research](https://scholariq.org/topics/sars-cov-2-and-covid-19-research/)
- [COVID-19 Clinical Research Studies](https://scholariq.org/topics/covid-19-clinical-research-studies/)
- [Diabetes and associated disorders](https://scholariq.org/topics/diabetes-and-associated-disorders/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.