# Blockade of the epidermal growth factor receptor signaling by a novel tyrosine kinase inhibitor leads to apoptosis of endothelial cells and therapy of human pancreatic carcinoma.

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/blockade-of-the-epidermal-growth-factor-receptor-signaling-by-a-novel-tyrosine/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Christiane J. Bruns,Carmen C. Solórzano,Matthew T. Harbison,Shutaro Ozawa,Rachel Tsan,Dominic Fan,James L. Abbruzzese,Peter Traxler,Elisabeth Buchdunger,Robert Radinsky,Isaiah J. Fidler |
| Citations | 501 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W1913061990 |
| PMID | 10850439 |
| Type | article |
| Year | 2000 |

## Paper authors

- [Christiane J. Bruns](https://scholariq.org/researchers/christiane-j-bruns/)

## Paper journal

- [PubMed](https://scholariq.org/journals/pubmed/)

## Paper primary topic

- [Angiogenesis and VEGF in Cancer](https://scholariq.org/topics/angiogenesis-and-vegf-in-cancer/)

## Paper topics

- [Angiogenesis and VEGF in Cancer](https://scholariq.org/topics/angiogenesis-and-vegf-in-cancer/)
- [Cancer, Hypoxia, and Metabolism](https://scholariq.org/topics/cancer-hypoxia-and-metabolism/)
- [Cancer Cells and Metastasis](https://scholariq.org/topics/cancer-cells-and-metastasis/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.