# Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/cardiac-hypertrophy-is-inhibited-by-antagonism-of-adam12-processing-of-hb-egf/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Masanori Asakura,Masafumi Kitakaze,Seiji Takashima,Yulin Liao,Fuminobu Ishikura,Tsuyoshi Yoshinaka,Hiroshi Ohmoto,Koichi Node,Kohichiro Yoshino,Hiroshi Ishiguro,Hiroshi Asanuma,Shoji Sanada,Yasushi Matsumura,Hiroshi Takeda,Shintaro Beppu,Michihiko Tada,Masatsugu Hori,Shigeki Higashiyama |
| Citations | 722 |
| DOI | 10.1038/nm0102-35 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2134533989 |
| PMID | 11786904 |
| Type | article |
| Year | 2002 |

## Paper authors

- [Masanori Asakura](https://scholariq.org/researchers/masanori-asakura/)
- [Masafumi Kitakaze](https://scholariq.org/researchers/masafumi-kitakaze/)

## Paper journal

- [Nature Medicine](https://scholariq.org/journals/nature-medicine/)

## Paper primary topic

- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)

## Paper topics

- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)
- [Cardiac Fibrosis and Remodeling](https://scholariq.org/topics/cardiac-fibrosis-and-remodeling/)
- [Signaling Pathways in Disease](https://scholariq.org/topics/signaling-pathways-in-disease/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.