# Catalytic in vivo protein knockdown by small-molecule PROTACs

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/catalytic-in-vivo-protein-knockdown-by-small-molecule-protacs/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Daniel P. Bondeson,Alina Mares,Ian E. Smith,Eunhwa Ko,Sébastien Campos,Afjal H. Miah,Katie E Mulholland,Natasha Routly,Dennis L. Buckley,Jeffrey L. Gustafson,Nico Zinn,Paola Grandi,Satoko Shimamura,Giovanna Bergamini,Maria Faelth-Savitski,Marcus Bantscheff,Carly S. Cox,Deborah A. Gordon,Ryan R. Willard,John J. Flanagan,Linda Casillas,Bartholomew J. Votta,Willem den Besten,Kristoffer Famm,Laurens Kruidenier,Paul S. Carter,John D. Harling,Ian Churcher,Craig M. Crews |
| Citations | 1,338 |
| DOI | 10.1038/nchembio.1858 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/4629852 |
| OpenAlex ID | https://openalex.org/W1512690422 |
| PMID | 26075522 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Ian E. Smith](https://scholariq.org/researchers/ian-e-smith/)

## Paper primary topic

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)

## Paper topics

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)
- [Peptidase Inhibition and Analysis](https://scholariq.org/topics/peptidase-inhibition-and-analysis/)
- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.