# CD4/CD8 T-Cell Selection Affects Chimeric Antigen Receptor (CAR) T-Cell Potency and Toxicity: Updated Results From a Phase I Anti-CD22 CAR T-Cell Trial

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/cd4-cd8-t-cell-selection-affects-chimeric-antigen-receptor-car-t-cell-potency/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Nirali N. Shah,Steven L. Highfill,Haneen Shalabi,Bonnie Yates,Jianjian Jin,Pamela L. Wolters,Amanda K. Ombrello,Seth M. Steinberg,Staci Martin,Cindy Delbrook,Leah Hoffman,Lauren Little,Anusha Ponduri,Haiying Qin,Haris Qureshi,Alina Dulau‐Florea,Dalia Salem,Hao‐Wei Wang,Constance M. Yuan,Maryalice Stetler‐Stevenson,Sandhya R. Panch,Minh Tran,Crystal L. Mackall,David F. Stroncek,Terry J. Fry |
| Citations | 421 |
| DOI | 10.1200/jco.19.03279 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/7280047 |
| OpenAlex ID | https://openalex.org/W3016233874 |
| PMID | 32286905 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Seth M. Steinberg](https://scholariq.org/researchers/seth-m-steinberg/)
- [Staci Martin](https://scholariq.org/researchers/staci-martin/)
- [Pamela L. Wolters](https://scholariq.org/researchers/pamela-l-wolters/)

## Paper journal

- [Journal of Clinical Oncology](https://scholariq.org/journals/journal-of-clinical-oncology/)

## Paper primary topic

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)

## Paper topics

- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)
- [Virus-based gene therapy research](https://scholariq.org/topics/virus-based-gene-therapy-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.