# CDK9 inhibition blocks the initiation of PINK1-PRKN-mediated mitophagy by regulating the SIRT1-FOXO3-BNIP3 axis and enhances the therapeutic effects involving mitochondrial dysfunction in hepatocellular carcinoma

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/cdk9-inhibition-blocks-the-initiation-of-pink1-prkn-mediated-mitophagy-by/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jingyue Yao,Jubo Wang,Ye Xu,Qinglong Guo,Yuening Sun,Jian Liu,Sichan Li,Yongjian Guo,Libin Wei |
| Citations | 267 |
| DOI | 10.1080/15548627.2021.2007027 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | hybrid |
| OA URL | https://doi.org/10.1080/15548627.2021.2007027 |
| OpenAlex ID | https://openalex.org/W4200053202 |
| PMID | 34890308 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Qinglong Guo](https://scholariq.org/researchers/qinglong-guo/)

## Paper primary topic

- [Autophagy in Disease and Therapy](https://scholariq.org/topics/autophagy-in-disease-and-therapy/)

## Paper topics

- [Autophagy in Disease and Therapy](https://scholariq.org/topics/autophagy-in-disease-and-therapy/)
- [Sirtuins and Resveratrol in Medicine](https://scholariq.org/topics/sirtuins-and-resveratrol-in-medicine/)
- [Endoplasmic Reticulum Stress and Disease](https://scholariq.org/topics/endoplasmic-reticulum-stress-and-disease/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.