# Celastrol reduces IL-1β induced matrix catabolism, oxidative stress and inflammation in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration in vivo

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/celastrol-reduces-il-1-induced-matrix-catabolism-oxidative-stress-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jian Chen,Jun Xuan,Yuntao Gu,Kesi Shi,Jun-Jun Xie,Jiaoxiang Chen,Zengming Zheng,Yu Chen,Xi-Bang Chen,Yaosen Wu,Xiaolei Zhang,Xiangyang Wang |
| Citations | 91 |
| DOI | 10.1016/j.biopha.2017.04.093 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2609830904 |
| PMID | 28458159 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Yu Chen](https://scholariq.org/researchers/yu-chen-5/)

## Paper journal

- [Biomedicine & Pharmacotherapy](https://scholariq.org/journals/biomedicine-and-pharmacotherapy/)

## Paper primary topic

- [Spine and Intervertebral Disc Pathology](https://scholariq.org/topics/spine-and-intervertebral-disc-pathology/)

## Paper topics

- [Spine and Intervertebral Disc Pathology](https://scholariq.org/topics/spine-and-intervertebral-disc-pathology/)
- [Pregnancy-related medical research](https://scholariq.org/topics/pregnancy-related-medical-research/)
- [Natural Compounds in Disease Treatment](https://scholariq.org/topics/natural-compounds-in-disease-treatment/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.