# Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/clinical-trials-in-amyotrophic-lateral-sclerosis-why-so-many-negative-trials-and/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Hiroshi Mitsumoto,Benjamin Rix Brooks,Vincenzo Silani |
| Citations | 291 |
| DOI | 10.1016/s1474-4422(14)70129-2 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2089034809 |
| PMID | 25316019 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Benjamin Rix Brooks](https://scholariq.org/researchers/benjamin-rix-brooks/)

## Paper primary topic

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)

## Paper topics

- [Amyotrophic Lateral Sclerosis Research](https://scholariq.org/topics/amyotrophic-lateral-sclerosis-research/)
- [Neurogenetic and Muscular Disorders Research](https://scholariq.org/topics/neurogenetic-and-muscular-disorders-research/)
- [Cholinesterase and Neurodegenerative Diseases](https://scholariq.org/topics/cholinesterase-and-neurodegenerative-diseases/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.