# Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/common-loss-of-function-variants-of-the-epidermal-barrier-protein-filaggrin-are/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Colin N A Palmer,Alan D. Irvine,Ana Terron-Kwiatkowski,Yiwei Zhao,Haihui Liao,Simon P. Lee,David Goudie,Aileen Sandilands,Linda Campbell,Frances J.D. Smith,Gráinne M. O’Regan,Rosemarie M. Watson,Joanne E. Cecil,Sherri J. Bale,John G. Compton,John J DiGiovanna,Philip Fleckman,Sue Lewis‐Jones,Gehan Arseculeratne,Ann Sergeant,Colin S. Munro,Brahim El Houate,Ken McElreavey,Liselotte Brydensholt Halkjær,Hans Bisgaard,Somnath Mukhopadhyay,W.H. Irwin McLean |
| Citations | 2,968 |
| DOI | 10.1038/ng1767 |
| Fields | Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2068176013 |
| PMID | 16550169 |
| Type | article |
| Year | 2006 |

## Paper authors

- [Alan D. Irvine](https://scholariq.org/researchers/alan-d-irvine/)

## Paper primary topic

- [Dermatology and Skin Diseases](https://scholariq.org/topics/dermatology-and-skin-diseases/)

## Paper topics

- [Dermatology and Skin Diseases](https://scholariq.org/topics/dermatology-and-skin-diseases/)
- [Allergic Rhinitis and Sensitization](https://scholariq.org/topics/allergic-rhinitis-and-sensitization/)
- [Food Allergy and Anaphylaxis Research](https://scholariq.org/topics/food-allergy-and-anaphylaxis-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.