# Comparisons between in-vitro and in-vivo metabolism of (S)-warfarin: catalytic activities of cDNA-expressed CYP2C9, its Leu359 variant and their mixture versus unbound clearance in patients with the corresponding CYP2C9 genotypes

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/comparisons-between-in-vitro-and-in-vivo-metabolism-of-s-warfarin-catalytic/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Harumi Takahashi,Toshitaka Kashima,Shinichi Nomoto,Kazunori Iwade,Hitoshi Tainaka,Teppei Shimizu,Yuko Nomizo,Nagisa Muramoto,Sosuke Kimura,Hirotoshi Echizen |
| Citations | 163 |
| DOI | 10.1097/00008571-199810000-00001 |
| Fields | Biochemistry, Genetics and Molecular Biology,Pharmacology, Toxicology and Pharmaceutics |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2150738344 |
| PMID | 9825828 |
| Type | article |
| Year | 1998 |

## Paper authors

- [Hirotoshi Echizen](https://scholariq.org/researchers/hirotoshi-echizen/)

## Paper primary topic

- [Pharmacogenetics and Drug Metabolism](https://scholariq.org/topics/pharmacogenetics-and-drug-metabolism/)

## Paper topics

- [Pharmacogenetics and Drug Metabolism](https://scholariq.org/topics/pharmacogenetics-and-drug-metabolism/)
- [Eicosanoids and Hypertension Pharmacology](https://scholariq.org/topics/eicosanoids-and-hypertension-pharmacology/)
- [Receptor Mechanisms and Signaling](https://scholariq.org/topics/receptor-mechanisms-and-signaling/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.