# Complementary genomic approaches highlight the PI3K/mTOR pathway as a common vulnerability in osteosarcoma

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/complementary-genomic-approaches-highlight-the-pi3k-mtor-pathway-as-a-common/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jennifer A. Perry,Adam Kieżun,Peter Tonzi,Eliezer M. Van Allen,Scott L. Carter,Sylvan C. Baca,Glenn S. Cowley,Ami S. Bhatt,Esther Rheinbay,Chandra Sekhar Pedamallu,Elena Helman,Amaro Taylor‐Weiner,Aaron McKenna,David S. DeLuca,Michael S. Lawrence,Lauren Ambrogio,Carrie Sougnez,Andrey Sivachenko,Loren D. Walensky,Nikhil Wagle,Jaume Mora,Carmen de Torres,Cinzia Lavarino,Simone dos Santos Aguiar,José Andrés Yunes,Sílvia Regina Brandalise,Gabriela Mercado,Jorge Meléndez-Zajgla,Rocío Cárdenas‐Cardós,Liliana Velasco‐Hidalgo,Charles W.M. Roberts,Levi A. Garraway,Carlos Rodríguez‐Galindo,Stacey Gabriel,Eric S. Lander,Todd R. Golub,Stuart H. Orkin,Gad Getz,Katherine A. Janeway |
| Citations | 508 |
| DOI | 10.1073/pnas.1419260111 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/111/51/E5564.full.pdf |
| OpenAlex ID | https://openalex.org/W2115160785 |
| PMID | 25512523 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Eliezer M. Van Allen](https://scholariq.org/researchers/eliezer-m-van-allen/)
- [Carlos Rodríguez‐Galindo](https://scholariq.org/researchers/carlos-rodriguez-galindo/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [CAR-T cell therapy research](https://scholariq.org/topics/car-t-cell-therapy-research/)
- [Sarcoma Diagnosis and Treatment](https://scholariq.org/topics/sarcoma-diagnosis-and-treatment/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.