# Concurrent RB1 and TP53 Alterations Define a Subset of EGFR-Mutant Lung Cancers at risk for Histologic Transformation and Inferior Clinical Outcomes

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/concurrent-rb1-and-tp53-alterations-define-a-subset-of-egfr-mutant-lung-cancers/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Michael Offin,Joseph M. Chan,Megan Tenet,Hira Rizvi,Ronglai Shen,Gregory J. Riely,Natasha Rekhtman,Yahya Daneshbod,Àlvaro Quintanal-Villalonga,Alexander Penson,Matthew D. Hellmann,Maria E. Arcila,Marc Ladanyi,Dana Pe’er,Mark G. Kris,Charles M. Rudin,Helena A. Yu |
| Citations | 458 |
| DOI | 10.1016/j.jtho.2019.06.002 |
| Fields | Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://www.ncbi.nlm.nih.gov/pmc/articles/6764905 |
| OpenAlex ID | https://openalex.org/W2952506496 |
| PMID | 31228622 |
| Type | article |
| Year | 2019 |

## Paper authors

- [Maria E. Arcila](https://scholariq.org/researchers/maria-e-arcila/)
- [Matthew D. Hellmann](https://scholariq.org/researchers/matthew-d-hellmann/)
- [Mark G. Kris](https://scholariq.org/researchers/mark-g-kris/)
- [Marc Ladanyi](https://scholariq.org/researchers/marc-ladanyi/)
- [Charles M. Rudin](https://scholariq.org/researchers/charles-m-rudin/)
- [Gregory J. Riely](https://scholariq.org/researchers/gregory-j-riely/)
- [Natasha Rekhtman](https://scholariq.org/researchers/natasha-rekhtman/)
- [Helena A. Yu](https://scholariq.org/researchers/helena-a-yu/)

## Paper funders

Showing 8 of 15.

- [Foundation for the National Institutes of Health](https://scholariq.org/funders/foundation-for-the-national-institutes-of-health/)
- [Amgen](https://scholariq.org/funders/amgen/)
- [Bristol-Myers Squibb](https://scholariq.org/funders/bristol-myers-squibb/)
- [Pfizer](https://scholariq.org/funders/pfizer/)
- [Bayer](https://scholariq.org/funders/bayer/)
- [Novartis](https://scholariq.org/funders/novartis/)
- [Celgene](https://scholariq.org/funders/celgene/)
- [AbbVie](https://scholariq.org/funders/abbvie/)

## Paper journal

- [Journal of Thoracic Oncology](https://scholariq.org/journals/journal-of-thoracic-oncology/)

## Paper primary topic

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)

## Paper topics

- [Lung Cancer Treatments and Mutations](https://scholariq.org/topics/lung-cancer-treatments-and-mutations/)
- [Lung Cancer Research Studies](https://scholariq.org/topics/lung-cancer-research-studies/)
- [Cancer-related Molecular Pathways](https://scholariq.org/topics/cancer-related-molecular-pathways/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.
