# Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/control-of-phosphorothioate-stereochemistry-substantially-increases-the-efficacy/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Naoki Iwamoto,David C. Butler,Nenad Svrzikapa,Susovan Mohapatra,Ivan Zlatev,Dinah W.Y. Sah,Meena Meena,Stephany M. Standley,Genliang Lu,Luciano H. Apponi,Maria Frank-Kamenetsky,Jason Jingxin Zhang,Chandra Vargeese,Gregory L. Verdine |
| Citations | 379 |
| DOI | 10.1038/nbt.3948 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W2746807303 |
| PMID | 28829437 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Naoki Iwamoto](https://scholariq.org/researchers/naoki-iwamoto/)

## Paper primary topic

- [DNA and Nucleic Acid Chemistry](https://scholariq.org/topics/dna-and-nucleic-acid-chemistry/)

## Paper topics

- [DNA and Nucleic Acid Chemistry](https://scholariq.org/topics/dna-and-nucleic-acid-chemistry/)
- [Advanced biosensing and bioanalysis techniques](https://scholariq.org/topics/advanced-biosensing-and-bioanalysis-techniques/)
- [RNA and protein synthesis mechanisms](https://scholariq.org/topics/rna-and-protein-synthesis-mechanisms/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.