# CRISPR-Cas9 treatment partially restores amyloid-β 42/40 in human fibroblasts with the Alzheimer’s disease PSEN1 M146L mutation

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/crispr-cas9-treatment-partially-restores-amyloid-42-40-in-human-fibroblasts-with/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Evangelos Konstantinidis,Agnieszka Molisak,Florian Perrin,Linn Streubel-Gallasch,Sarah M. Fayad,Daniel Y. Kim,Karl Petri,Martin J. Aryee,Ximena Aguilar,Bence György,Vilmantas Giedraitis,J. Keith Joung,Vikram Pattanayak,Magnus Essand,Anna Erlandsson,Oksana Berezovska,Martin Ingelsson |
| Citations | 51 |
| DOI | 10.1016/j.omtn.2022.03.022 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | http://www.cell.com/article/S2162253122000713/pdf |
| OpenAlex ID | https://openalex.org/W4220704556 |
| PMID | 35505961 |
| Type | article |
| Year | 2022 |

## Paper authors

- [Ximena Aguilar](https://scholariq.org/researchers/ximena-aguilar/)

## Paper primary topic

- [CRISPR and Genetic Engineering](https://scholariq.org/topics/crispr-and-genetic-engineering/)

## Paper topics

- [CRISPR and Genetic Engineering](https://scholariq.org/topics/crispr-and-genetic-engineering/)
- [Genetics, Aging, and Longevity in Model Organisms](https://scholariq.org/topics/genetics-aging-and-longevity-in-model-organisms/)
- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.