# Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/crystal-structures-of-pi3k-complexed-with-pi103-and-its-derivatives-new/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Yanlong Zhao,Xi Zhang,Ying‐Yi Chen,Shaoyong Lu,Yuefeng Peng,Xiang Wang,Chengliang Guo,Aiwu Zhou,Jingmiao Zhang,Jingmiao Zhang,Yu Luo,Qiancheng Shen,Jian Ding,Linghua Meng,Jian Zhang,Jian Zhang |
| Citations | 102 |
| DOI | 10.1021/ml400378e |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2mk6fb6 |
| OpenAlex ID | https://openalex.org/W2001669845 |
| PMID | 24900786 |
| Type | article |
| Year | 2013 |

## Paper authors

- [Ying‐Yi Chen](https://scholariq.org/researchers/ying-yi-chen/)

## Paper primary topic

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

## Paper topics

- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Chronic Lymphocytic Leukemia Research](https://scholariq.org/topics/chronic-lymphocytic-leukemia-research/)
- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.