# CSF1/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/csf1-csf1r-signaling-inhibitor-pexidartinib-plx3397-reprograms-tumor-associated/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Tomohiro Fujiwara,Mohamed A. Yakoub,Andrew Chandler,Alexander B. Christ,Guangli Yang,Ouathek Ouerfelli,Vinagolu K. Rajasekhar,Aki Yoshida,Hiroya Kondo,Toshiaki Hata,Hiroshi Tazawa,Yildirim Dogan,Malcolm A.S. Moore,Toshiyoshi Fujiwara,Toshifumi Ozaki,Ed Purdue,John H. Healey |
| Citations | 269 |
| DOI | 10.1158/1535-7163.mct-20-0591 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://aacrjournals.org/mct/article-pdf/20/8/1388/3106368/1388.pdf |
| OpenAlex ID | https://openalex.org/W3164752908 |
| PMID | 34088832 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Tomohiro Fujiwara](https://scholariq.org/researchers/tomohiro-fujiwara/)

## Paper primary topic

- [Sarcoma Diagnosis and Treatment](https://scholariq.org/topics/sarcoma-diagnosis-and-treatment/)

## Paper topics

- [Sarcoma Diagnosis and Treatment](https://scholariq.org/topics/sarcoma-diagnosis-and-treatment/)
- [Immune cells in cancer](https://scholariq.org/topics/immune-cells-in-cancer/)
- [Immune Cell Function and Interaction](https://scholariq.org/topics/immune-cell-function-and-interaction/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.