# de novo MAPT mutation G335A causes severe brain atrophy, 3R and 4R PHF-tau pathology and early onset frontotemporal dementia

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/de-novo-mapt-mutation-g335a-causes-severe-brain-atrophy-3r-and-4r-phf-tau/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Kunié Ando,Lorenzo Ferlini,Valérie Suain,Zehra Yilmaz,Salwa Mansour,Isabelle Le Ber,Cécile Bouchard,Karelle Leroy,Alexandra Dürr,Fabienne Clot,Marie Sarazin,Jean‐Christophe Bier,Jean‐Pierre Brion |
| Citations | 17 |
| DOI | 10.1186/s40478-020-00977-8 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | gold |
| OA URL | https://actaneurocomms.biomedcentral.com/track/pdf/10.1186/s40478-020-00977-8 |
| OpenAlex ID | https://openalex.org/W3037848172 |
| PMID | 32600421 |
| Type | article |
| Year | 2020 |

## Paper authors

- [Jean‐Christophe Bier](https://scholariq.org/researchers/jean-christophe-bier/)

## Paper primary topic

- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)

## Paper topics

- [Alzheimer's disease research and treatments](https://scholariq.org/topics/alzheimer-s-disease-research-and-treatments/)
- [Cerebrovascular and genetic disorders](https://scholariq.org/topics/cerebrovascular-and-genetic-disorders/)
- [Mitochondrial Function and Pathology](https://scholariq.org/topics/mitochondrial-function-and-pathology/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.