# Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/direct-activation-of-rip3-mlkl-dependent-necrosis-by-herpes-simplex-virus-1-hsv/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Xing Wang,Yun Li,Shan Liu,Xiaoliang Yu,Lin Li,Cuilin Shi,Wenhui He,Jun Li,Lei Xu,Zhilin Hu,Lu Yu,Zhongxu Yang,Qin Chen,Lin Ge,Zili Zhang,Biqi Zhou,Xuejun Jiang,She Chen,Sudan He |
| Citations | 229 |
| DOI | 10.1073/pnas.1412767111 |
| Fields | Immunology and Microbiology,Medicine |
| Open Access | true |
| OA Status | bronze |
| OA URL | https://www.pnas.org/content/pnas/111/43/15438.full.pdf |
| OpenAlex ID | https://openalex.org/W2076658768 |
| PMID | 25316792 |
| Type | article |
| Year | 2014 |

## Paper authors

- [Zili Zhang](https://scholariq.org/researchers/zili-zhang/)

## Paper journal

- [Proceedings of the National Academy of Sciences](https://scholariq.org/journals/proceedings-of-the-national-academy-of-sciences/)

## Paper primary topic

- [Herpesvirus Infections and Treatments](https://scholariq.org/topics/herpesvirus-infections-and-treatments/)

## Paper topics

- [Herpesvirus Infections and Treatments](https://scholariq.org/topics/herpesvirus-infections-and-treatments/)
- [interferon and immune responses](https://scholariq.org/topics/interferon-and-immune-responses/)
- [Immune Response and Inflammation](https://scholariq.org/topics/immune-response-and-inflammation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.