# Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/directly-reprogrammed-human-neurons-retain-aging-associated-transcriptomic/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jérôme Mertens,Apuã C.M. Paquola,Manching Ku,Emily M. Hatch,Lena Böhnke,Shauheen Ladjevardi,Sean McGrath,Benjamin C. Campbell,Hyungjun Lee,Joseph R. Herdy,J. Tiago Gonçalves,Tomohisa Toda,Yongsung Kim,Jürgen Winkler,Jun Yao,Martin W. Hetzer,Fred H. Gage |
| Citations | 771 |
| DOI | 10.1016/j.stem.2015.09.001 |
| Fields | Biochemistry, Genetics and Molecular Biology |
| Open Access | true |
| OA Status | bronze |
| OA URL | http://www.cell.com/article/S1934590915004087/pdf |
| OpenAlex ID | https://openalex.org/W1806909159 |
| PMID | 26456686 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Yongsung Kim](https://scholariq.org/researchers/yongsung-kim/)

## Paper primary topic

- [RNA Research and Splicing](https://scholariq.org/topics/rna-research-and-splicing/)

## Paper topics

- [RNA Research and Splicing](https://scholariq.org/topics/rna-research-and-splicing/)
- [Genomics and Chromatin Dynamics](https://scholariq.org/topics/genomics-and-chromatin-dynamics/)
- [Pluripotent Stem Cells Research](https://scholariq.org/topics/pluripotent-stem-cells-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.