# Discovery of 2-((3-Acrylamido-4-methylphenyl)amino)-<i>N</i>-(2-methyl-5-(3,4,5-trimethoxybenzamido)phenyl)-4-(methylamino)pyrimidine-5-carboxamide (CHMFL-BMX-078) as a Highly Potent and Selective Type II Irreversible Bone Marrow Kinase in the X Chromosome (BMX) Kinase Inhibitor

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-2-3-acrylamido-4-methylphenyl-amino-i-n-i-2-methyl-5-3-4-5/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Xiaofei Liang,Fengchao Lv,Beilei Wang,Kailin Yu,Wu Hong,Ziping Qi,Zongru Jiang,Cheng Chen,Aoli Wang,Weili Miao,Wenchao Wang,Zhenquan Hu,Juan Liu,Xiaochuan Liu,Xiaochuan Liu,Zheng Zhao,Li Wang,Shanchuan Zhang,Zi Ye,Chu Wang,Tao Ren,Yinsheng Wang,Qingsong Liu,Jing Liu,Jing Liu |
| Citations | 27 |
| DOI | 10.1021/acs.jmedchem.6b01413 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2gh9m74 |
| OpenAlex ID | https://openalex.org/W2585109524 |
| PMID | 28140585 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Zi Ye](https://scholariq.org/researchers/zi-ye/)

## Paper primary topic

- [Chronic Lymphocytic Leukemia Research](https://scholariq.org/topics/chronic-lymphocytic-leukemia-research/)

## Paper topics

- [Chronic Lymphocytic Leukemia Research](https://scholariq.org/topics/chronic-lymphocytic-leukemia-research/)
- [Chronic Myeloid Leukemia Treatments](https://scholariq.org/topics/chronic-myeloid-leukemia-treatments/)
- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.