# Discovery of 5-\[\[4-\[(2,3-Dimethyl-2<i>H</i>-indazol-6-yl)methylamino\]-2-pyrimidinyl\]amino\]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-5-4-2-3-dimethyl-2-i-h-i-indazol-6-yl-methylamino-2-pyrimidinyl/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Philip A. Harris,Amogh Boloor,Mui Cheung,Rakesh Kumar,Renae M. Crosby,Ronda G. Davis‐Ward,Andrea H. Epperly,Kevin W. Hinkle,R. Hunter,Jennifer H. Johnson,Victoria B. Knick,Christopher P. Laudeman,Deirdre K. Luttrell,Robert A. Mook,Robert T. Nolte,Sharon K. Rudolph,Jerzy R. Szewczyk,Anne T. Truesdale,James M. Veal,Liping Wang,Jeffrey A. Stafford |
| Citations | 347 |
| DOI | 10.1021/jm800566m |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q26971xr |
| OpenAlex ID | https://openalex.org/W2035387891 |
| PMID | 18620382 |
| Type | article |
| Year | 2008 |

## Paper authors

- [Liping Wang](https://scholariq.org/researchers/liping-wang/)

## Paper primary topic

- [Angiogenesis and VEGF in Cancer](https://scholariq.org/topics/angiogenesis-and-vegf-in-cancer/)

## Paper topics

- [Angiogenesis and VEGF in Cancer](https://scholariq.org/topics/angiogenesis-and-vegf-in-cancer/)
- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [Cancer Treatment and Pharmacology](https://scholariq.org/topics/cancer-treatment-and-pharmacology/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.