# Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-a-first-in-class-receptor-interacting-protein-1-rip1-kinase/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Philip A. Harris,Scott B. Berger,Jae Uk Jeong,Rakesh Nagilla,Deepak Bandyopadhyay,Nino Campobasso,Carol A. Capriotti,Julie A. Cox,Lauren Dare,Xiaoyang Dong,Patrick M. Eidam,Joshua N. Finger,Sandra J. Hoffman,James Kang,Viera Kasparcova,Bryan W. King,Ruth Lehr,Yunfeng Lan,Lara K. Leister,John D. Lich,Thomas T. MacDonald,Nathan A. Miller,Michael T. Ouellette,Christina Pao,A. H. ABD EL RAHMAN,Michael Reilly,Alan R. Rendina,Elizabeth J. Rivera,Michelle C. Schaeffer,Clark A. Sehon,Robert R. Singhaus,Helen H. Sun,Barbara A. Swift,Rachel D. Totoritis,Anna Vossenkämper,Paris Ward,David D. Wisnoski,Daohua Zhang,Robert W. Marquis,Peter J. Gough,John Bertin |
| Citations | 480 |
| DOI | 10.1021/acs.jmedchem.6b01751 |
| Fields | Biochemistry, Genetics and Molecular Biology,Immunology and Microbiology |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2sq92nr |
| OpenAlex ID | https://openalex.org/W2584580415 |
| PMID | 28151659 |
| Type | article |
| Year | 2017 |

## Paper authors

- [Christina Pao](https://scholariq.org/researchers/christina-pao/)

## Paper primary topic

- [Cell death mechanisms and regulation](https://scholariq.org/topics/cell-death-mechanisms-and-regulation/)

## Paper topics

- [Cell death mechanisms and regulation](https://scholariq.org/topics/cell-death-mechanisms-and-regulation/)
- [interferon and immune responses](https://scholariq.org/topics/interferon-and-immune-responses/)
- [Immune Response and Inflammation](https://scholariq.org/topics/immune-response-and-inflammation/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.