# Discovery of a Novel Orally Bioavailable FLT3-PROTAC Degrader for Efficient Treatment of Acute Myeloid Leukemia and Overcoming Resistance of FLT3 Inhibitors

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-a-novel-orally-bioavailable-flt3-protac-degrader-for-efficient/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Junwei Wang,Quanjin Rong,Lei Ye,Bingqian Fang,Yifan Zhao,Yu Sun,Haikun Zhou,Dan Wang,Jinting He,Zhenzhen Cui,Qijian Zhang,Di Kang,Lihong Hu |
| Citations | 30 |
| DOI | 10.1021/acs.jmedchem.4c00051 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | false |
| OA Status | closed |
| OpenAlex ID | https://openalex.org/W4395075610 |
| PMID | 38655686 |
| Type | article |
| Year | 2024 |

## Paper authors

- [Di Kang](https://scholariq.org/researchers/di-kang/)

## Paper primary topic

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)

## Paper topics

- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)
- [Multiple Myeloma Research and Treatments](https://scholariq.org/topics/multiple-myeloma-research-and-treatments/)
- [Ubiquitin and proteasome pathways](https://scholariq.org/topics/ubiquitin-and-proteasome-pathways/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.