# Discovery of a Potent and Selective FLT3 Inhibitor (<i>Z</i>)-<i>N</i>-(5-((5-Fluoro-2-oxoindolin-3-ylidene)methyl)-4-methyl-1<i>H</i>-pyrrol-3-yl)-3-(pyrrolidin-1-yl)propanamide with Improved Drug-like Properties and Superior Efficacy in FLT3-ITD-Positive Acute Myeloid Leukemia

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-a-potent-and-selective-flt3-inhibitor-i-z-i-i-n-i-5-5-fluoro-2/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Junwei Wang,Xiang Pan,Yi Song,Jian Liu,Fei Ma,Ping Wang,Yan Liu,Lin Zhao,Di Kang,Lihong Hu |
| Citations | 29 |
| DOI | 10.1021/acs.jmedchem.0c02247 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q29g5rkv |
| OpenAlex ID | https://openalex.org/W3145256917 |
| PMID | 33797247 |
| Type | article |
| Year | 2021 |

## Paper authors

- [Di Kang](https://scholariq.org/researchers/di-kang/)

## Paper primary topic

- [Acute Myeloid Leukemia Research](https://scholariq.org/topics/acute-myeloid-leukemia-research/)

## Paper topics

- [Acute Myeloid Leukemia Research](https://scholariq.org/topics/acute-myeloid-leukemia-research/)
- [Protein Degradation and Inhibitors](https://scholariq.org/topics/protein-degradation-and-inhibitors/)
- [HIV/AIDS drug development and treatment](https://scholariq.org/topics/hiv-aids-drug-development-and-treatment/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.