# Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-az0108-an-orally-bioavailable-phthalazinone-parp-inhibitor-that/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Jeffrey W. Johannes,Lynsie Almeida,Kevin Daly,Andrew D. Ferguson,Shaun Grosskurth,Huiping Guan,Tina Howard,Stephanos Ioannidis,Steven L. Kazmirski,Michelle L. Lamb,Nicholas Larsen,Paul D. Lyne,Keith Mikule,Claude A. Ogoe,Bo Peng,Philip Petteruti,Jon Read,Nancy Su,Mark Sylvester,Scott Throner,Wenxian Wang,Xin Wang,Jiaquan Wu,Qing Ye,Yan Yu,Xiaolan Zheng,David A. Scott |
| Citations | 63 |
| DOI | 10.1016/j.bmcl.2015.10.079 |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2wh2t0j |
| OpenAlex ID | https://openalex.org/W1871990940 |
| PMID | 26546219 |
| Type | article |
| Year | 2015 |

## Paper authors

- [Kevin Daly](https://scholariq.org/researchers/kevin-daly/)
- [Wenxian Wang](https://scholariq.org/researchers/wenxian-wang/)

## Paper primary topic

- [PARP inhibition in cancer therapy](https://scholariq.org/topics/parp-inhibition-in-cancer-therapy/)

## Paper topics

- [PARP inhibition in cancer therapy](https://scholariq.org/topics/parp-inhibition-in-cancer-therapy/)
- [Microtubule and mitosis dynamics](https://scholariq.org/topics/microtubule-and-mitosis-dynamics/)
- [Signaling Pathways in Disease](https://scholariq.org/topics/signaling-pathways-in-disease/)

---
Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.