# Discovery of<i>N</i>-(4-(3-Amino-1<i>H</i>-indazol-4-yl)phenyl)-<i>N</i>‘-(2-fluoro-5-methylphenyl)urea (ABT-869), a 3-Aminoindazole-Based Orally Active Multitargeted Receptor Tyrosine Kinase Inhibitor

**Type:** Papers  
**Canonical URL:** https://scholariq.org/papers/discovery-of-i-n-i-4-3-amino-1-i-h-i-indazol-4-yl-phenyl-i-n-i-2-fluoro-5/

## Facts

| Field | Value |
| --- | --- |
| Author Names | Yujia Dai,Kresna Hartandi,Zhiqin Ji,Asma A. Ahmed,Daniel H. Albert,Joy Bauch,Jennifer J. Bouska,Peter F. Bousquet,George A. Cunha,Keith B. Glaser,Christopher M. Harris,Dean Hickman,Jun Guo,Junling Li,Patrick A. Marcotte,Kennan C. Marsh,Maria D. Moskey,Ruth L. Martin,Amanda M. Olson,Donald J. Osterling,Lori J. Pease,Niru B. Soni,Kent D. Stewart,Vincent S. Stoll,Paul Tapang,David R. Reuter,Steven K. Davidsen,Michael R. Michaelides |
| Citations | 187 |
| DOI | 10.1021/jm061280h |
| Fields | Biochemistry, Genetics and Molecular Biology,Medicine |
| Open Access | true |
| OA Status | green |
| OA URL | https://doi.org/10.7270/q2dj5f95 |
| OpenAlex ID | https://openalex.org/W2031498310 |
| PMID | 17343372 |
| Type | article |
| Year | 2007 |

## Paper authors

- [Junling Li](https://scholariq.org/researchers/junling-li/)

## Paper primary topic

- [Angiogenesis and VEGF in Cancer](https://scholariq.org/topics/angiogenesis-and-vegf-in-cancer/)

## Paper topics

- [Angiogenesis and VEGF in Cancer](https://scholariq.org/topics/angiogenesis-and-vegf-in-cancer/)
- [PI3K/AKT/mTOR signaling in cancer](https://scholariq.org/topics/pi3k-akt-mtor-signaling-in-cancer/)
- [HER2/EGFR in Cancer Research](https://scholariq.org/topics/her2-egfr-in-cancer-research/)

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Source: ScholarIQ — public research metadata, principally OpenAlex. See https://scholariq.org/sources/ for provenance and https://scholariq.org/methodology/ for what these figures mean.